LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974
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چکیده
منابع مشابه
LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974
In this study, LPS-induced inflammatory responses in BEAS-2B human bronchial epithelial cells and human umbilical vein endothelial cell (HUVEC)s were found to be prevented by Dickkopf-1 (DKK-1), a secreted Wnt antagonist, and LGK974, a small molecular inhibitor of the Wnt secretion. LPS-induced IκB degradation and NF-κB nuclear translocation as well as the expressions of pro-inflammatory genes ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/srep41612